Novel biomarkers and therapeutic approaches for diabetic retinopathy and nephropathy: Recent progress and future perspectives

Ziyan Xie; Xinhua Xiao

doi:10.3389/fendo.2022.1065856

Novel biomarkers and therapeutic approaches for diabetic retinopathy and nephropathy: Recent progress and future perspectives

Front Endocrinol (Lausanne). 2022 Nov 25:13:1065856. doi: 10.3389/fendo.2022.1065856. eCollection 2022.

Authors

Ziyan Xie¹, Xinhua Xiao¹

Affiliation

¹ Department of Endocrinology, Key Laboratory of Endocrinology, Ministry of Health, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.

Abstract

The global burden due to microvascular complications in patients with diabetes mellitus persists and even increases alarmingly, the intervention and management are now encountering many difficulties and challenges. This paper reviews the recent advancement and progress in novel biomarkers, artificial intelligence technology, therapeutic agents and approaches of diabetic retinopathy and nephropathy, providing more insights into the management of microvascular complications.

Keywords: artificial intelligence; biomarkers; diabetic nephropathy; diabetic retinopathy; microvascular complications; therapy.

Publication types

Review
Research Support, Non-U.S. Gov't

MeSH terms

Artificial Intelligence
Diabetes Mellitus*
Diabetic Nephropathies* / etiology
Diabetic Nephropathies* / therapy
Diabetic Retinopathy* / diagnosis
Diabetic Retinopathy* / therapy
Humans