Main Causal Agents of Occupational Asthma in France, Reported to the National Network for Occupational Disease Vigilance and Prevention (RNV3P) 2001-2018

Ann Work Expo Health. 2023 Mar 15;67(3):297-302. doi: 10.1093/annweh/wxac079.

Abstract

Objectives: The definition of work-related Asthma (WRA) has changed in recent years and new etiologies and agents have been identified. The aim of this study is to describe the main causal agents of WRA in France in the period 2001-2018 in the main work sectors.

Methods: Data were collected from the French national network of occupational health surveillance and prevention [Réseau National de Vigilance et de Prévention des Pathologies Professionnelles (RNV3P)], Data between 2001 and 2018 with at least a probable or certain association with one occupational agent, were included.

Results: Work sectors with more cases OF WRA included personal service activities (10.6%), food industry (10.2%) and healthcare activities (7.6%). WRA cases were most frequently related to flour (10%), quaternary ammoniums compounds (5.3%), isocyanates (5.1%) and cleaning products (4.8%).

Conclusion: Occupational exposure to specific agents capable of causing WRA is still present, and four agents represent more than 25% of the cases. Actions to prevent respiratory exposure are still relevant.

Keywords: causal agents; national network; occupational asthma.

MeSH terms

  • Asthma, Occupational* / epidemiology
  • Asthma, Occupational* / etiology
  • Asthma, Occupational* / prevention & control
  • Flour
  • France / epidemiology
  • Humans
  • Occupational Diseases* / epidemiology
  • Occupational Diseases* / prevention & control
  • Occupational Exposure*