Lipid nanoparticles for oral delivery of nucleic acids for treating inflammatory bowel disease

Chunhua Yang; Gianfranco Alpini; Shannon Glaser; Didier Merlin

doi:10.2217/nnm-2022-0222

Lipid nanoparticles for oral delivery of nucleic acids for treating inflammatory bowel disease

Nanomedicine (Lond). 2022 Sep;17(21):1501-1504. doi: 10.2217/nnm-2022-0222. Epub 2022 Nov 1.

Authors

Chunhua Yang^{1

2}, Gianfranco Alpini^{3

4}, Shannon Glaser⁵, Didier Merlin^{1

2}

Affiliations

¹ Institute for Biomedical Sciences, Digestive Disease Research Group, Georgia State University, Atlanta, GA 30303, USA.
² Research, Atlanta Veterans Affairs Medical Center, Decatur, GA 30302, USA.
³ Department of Medicine, Division of Gastroenterology & Hepatology, Indiana University School of Medicine, Indianapolis, IN 46220, USA.
⁴ Research, Richard L. Roudebush VA Medical Center, Indianapolis, IN 46202, USA.
⁵ Department of Medical Physiology, Texas A&M University School of Medicine, Bryan, TX 77807, USA.

PMID: 36317587
DOI: 10.2217/nnm-2022-0222

No abstract available

Keywords: Crohn's disease; gene therapy; plant-derived lipid nanoparticles; solid lipid nanoparticles; targeted drug delivery; ulcerative colitis.

Publication types

Editorial
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Colitis, Ulcerative*
Humans
Inflammatory Bowel Diseases* / drug therapy
Nanoparticles*
Nucleic Acids* / therapeutic use

Substances

Lipid Nanoparticles
Nucleic Acids

Publication types

MeSH terms

Substances

Grants and funding