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Am J Psychiatry. 1987 Sep;144(9):1218-20.

Association of elevated plasma anticholinergic activity with delirium in surgical patients.


In a surgical intensive care unit, plasma anticholinergic activity was significantly higher in nine delirious patients than in 16 patients without delirium. The delirium may have been related to medications that are known to be associated with delirium and/or anticholinergic activity.

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