Human platelet factor 4 gene is mapped to 4q12----...[Cytogenet Cell Genet. 1987]

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1: Cytogenet Cell Genet. 1987;45(2):67-9.Links

Human platelet factor 4 gene is mapped to 4q12----q21.

Griffin CA, Emanuel BS, LaRocco P, Schwartz E, Poncz M.

The gene for human platelet factor 4 has been mapped to the q12----q21 region of chromosome 4 by in situ hybridization. Hybridization of the same probe to leukemic cells carrying a t(4;11)(q21;q23) showed that the human platelet factor 4 gene is proximal to the breakpoint on chromosome 4.

PMID: 3622011 [PubMed - indexed for MEDLINE]

Interferon-inducible gene maps to a chromosomal band associated with a (4;11) translocation in acute leukemia cells. [Proc Natl Acad Sci U S A. 1987]
Monocyte-derived neutrophil chemotactic factor (MDNCF/IL-8) resides in a gene cluster along with several other members of the platelet factor 4 gene superfamily. [Hum Genet. 1990]
Human gene coding for granulocyte-colony stimulating factor is assigned to the q21-q22 region of chromosome 17. [Somat Cell Mol Genet. 1987]
The human basic fibroblast growth factor gene is located on the long arm of chromosome 4 at bands q26-q27. [Oncogene Res. 1990]
Human platelet basic protein/connective tissue activating peptide-III maps in a gene cluster on chromosome 4q12-q13 along with other genes of the beta-thromboglobulin superfamily. [Hum Genet. 1991]
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Human platelet factor 4 gene is mapped to 4q12----q21.

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