J Clin Exp Neuropsychol. 1987 Aug;9(4):399-406.

Wilson's disease, a reversible dementia: case report.

Rosselli M, Lorenzana P, Rosselli A, Vergara I.

Abstract

A case of advanced Wilson's disease with clear dementing features is presented. Neuropsychological evaluation before treatment revealed intellectual deterioration particularly in memory and performance tasks. The patient was treated with Penicillamine, a copper-chelating agent, for 7 months, with notable improvement in her dementia and in her motor signs. A second battery of neuropsychological tests demonstrated the improvement in the mental aspects. These findings support the concept of Wilson's disease being a reversible dementia.

PMID:: 3597731; [PubMed - indexed for MEDLINE]

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Penicillamine

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