The majority of choroidal tumours are diagnosed accurately with clinical examination and the additional data obtained from non-invasive imaging techniques. Choroidal biopsies may be undertaken for diagnostic clarity in cases such as small melanocytic or indeterminate lesions, identifying the primary tumour in the case of choroidal metastases or the subclassification of rarer conditions such as uveal lymphoma. There is however an increasing use of biopsy techniques for prognostication in uveal melanoma. This review explores the main indications and surgical techniques for tumour acquisition, and the optimised approach utilised by the current authors to improve successful yield for histological and genetic analysis.
摘要: 大多数脉络膜肿瘤通过临床检查和非侵入性成像技术所获得的额外数据可得到准确诊断。对于小的黑色素细胞或不确定的病变, 可进行脉络膜活检以明确诊断, 以在脉络膜转移或更罕见疾病 (如葡萄膜淋巴瘤) 的亚类的情况下确定原发肿瘤。但是目前已经越来越多地使用活检技术来预测葡萄膜黑色素瘤的预后。本综述探索了脉络膜活检获取肿瘤组织的主要适应症和手术技术, 并总结了当前学者们为提高组织学和遗传分析学的成功率而使用的优化方法。.
© 2022. The Author(s), under exclusive licence to The Royal College of Ophthalmologists.