Neural basis of prosocial behavior

Trends Neurosci. 2022 Oct;45(10):749-762. doi: 10.1016/j.tins.2022.06.008. Epub 2022 Jul 16.

Abstract

The ability to behave in ways that benefit other individuals' well-being is among the most celebrated human characteristics crucial for social cohesiveness. Across mammalian species, animals display various forms of prosocial behaviors - comforting, helping, and resource sharing - to support others' emotions, goals, and/or material needs. In this review, we provide a cross-species view of the behavioral manifestations, proximate and ultimate drives, and neural mechanisms of prosocial behaviors. We summarize key findings from recent studies in humans and rodents that have shed light on the neural mechanisms underlying different processes essential for prosocial interactions, from perception and empathic sharing of others' states to prosocial decisions and actions.

Keywords: amygdala; anterior cingulate cortex; comforting; empathy; helping; neural circuit.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't
  • Research Support, N.I.H., Extramural

MeSH terms

  • Altruism*
  • Animals
  • Emotions
  • Empathy
  • Humans
  • Mammals
  • Social Behavior*