Am J Psychiatry. 1987 May;144(5):664-5.

Emergence of depressive symptoms in patients receiving alprazolam for panic disorder.

Lydiard RB, Laraia MT, Ballenger JC, Howell EF.

Abstract

The authors relate their clinical experience with 46 panic disorder patients who were receiving 3-10 mg/day of alprazolam. Fifteen (33%) developed symptoms consistent with DSM-III criteria for major depression despite remission of their panic symptoms. Clinicians should be alert to this potentially reversible complication.

PMID:: 3578580; [PubMed - indexed for MEDLINE]

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