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Dynamics of follicular growth in the human: a model from preliminary results.
In the human species, follicle growth is a very long process. The ovulatory follicle originates from a cohort of pre-antral follicles that have differentiated their theca interna 85 days earlier under the control of the high peri-ovulatory steroid and gonadotrophin levels. During growth the number of follicles decreases by atresia under the influence of factors relating to the size of the follicles. Their growth rate is regulated by intra- and extra-ovarian hormonal factors. At the end of the luteal phase, 15-20 days before ovulation, the next ovulatory follicle is recruited among a follicle population of 2-5 mm in diameter. At the beginning of the menstrual cycle it can be distinguished only by its size; a few days later it starts its maturation and exhibits its dominance on the other healthy follicles present in the two ovaries.
PMID: 3558758 [PubMed - indexed for MEDLINE]
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Cited by 5 PubMed Central articles
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ReviewCryopreservation/transplantation of ovarian tissue and in vitro maturation of follicles and oocytes: challenges for fertility preservation.
Varghese AC, du Plessis SS, Falcone T, Agarwal A.
Reprod Biol Endocrinol. 2008 Oct 2; 6:47. Epub 2008 Oct 2.
[Reprod Biol Endocrinol. 2008]
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Genomewide discovery and classification of candidate ovarian fertility genes in the mouse.
Gallardo TD, John GB, Shirley L, Contreras CM, Akbay EA, Haynie JM, Ward SE, Shidler MJ, Castrillon DH.
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[Genetics. 2007]
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Comparative analysis of follicle morphology and oocyte diameter in four mammalian species (mouse, hamster, pig, and human).
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[J Exp Clin Assist Reprod. 2006]
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