Isolation and characterization of a Streptococcus mutans bacteriocin inhibitor from Streptococcus pyogenes

Infect Immun. 1978 May;20(2):578-80. doi: 10.1128/iai.20.2.578-580.1978.

Abstract

An inhibitor of Streptococcus mutans strain GS5 bacteriocin was released from a bacteriocin-sensitive strain of S. pyogenes by sonic treatment and partly purified by gel filtration on a Sepharose 6B column. The inhibitory factor was sensitive to heat, trypsin, and periodate and possessed a molecular weight of approximately 93,000. This factor may be the receptor for the S. mutans bacteriocin.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Bacterial Proteins / isolation & purification
  • Bacterial Proteins / pharmacology
  • Bacteriocins / antagonists & inhibitors*
  • Cell Wall / analysis
  • Glycoproteins / isolation & purification
  • Glycoproteins / pharmacology
  • Molecular Weight
  • Receptors, Drug / isolation & purification*
  • Streptococcus mutans*
  • Streptococcus pyogenes / analysis*

Substances

  • Bacterial Proteins
  • Bacteriocins
  • Glycoproteins
  • Receptors, Drug