Clinical electrophysiology of the aging heart

Expert Rev Cardiovasc Ther. 2022 Feb;20(2):123-139. doi: 10.1080/14779072.2022.2045196. Epub 2022 Mar 14.

Abstract

Introduction: Advancements in medical and consumer-grade technologies have made it easier than ever to monitor a patient's heart rhythm and to diagnose arrhythmias. Octogenarians with symptomatic arrhythmias have unique management challenges due to their frailty, complex drug interactions, cognitive impairment, and competing comorbidities. The management decisions are further complicated by the lack of randomized evidence to guide treatment.

Areas covered: A comprehensive literature review was undertaken to outline various tachyarrhythmias and bradyarrhythmias and their management, the role of cardiac implantable electronic devices, cardiac ablations, and specific geriatric arrhythmia considerations as recommended in international guidelines.

Expert opinion: Atrial fibrillation (AF) is arguably the most important arrhythmia in the elderly and is associated with significant morbidity and mortality. Early diagnosis of AF, potentially with smart devices (wearables), has the potential to reduce the incidence of stroke, systemic emboli, and the risk of dementia. Bradyarrhythmias have a high incidence in the elderly as well, often requiring implantation of a permanent pacemaker. Leadless pacemakers implanted directly into the right ventricle are great options for gaining traction in elderly patients.

Keywords: ablation; antiarrhythmic drugs; arrhythmias; elderly; electrophysiology; geriatrics; pacemaker.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Aging
  • Atrial Fibrillation* / surgery
  • Catheter Ablation*
  • Heart
  • Humans
  • Pacemaker, Artificial*