Abstract
A double-blind, placebo-controlled crossover study was conducted to examine the effects of pindolol for the treatment of 11 patients with impulsive, explosive behaviors and other emotional-behavioral abnormalities as a consequence of brain disease or injury. Pindolol treatment was associated with significant therapeutic benefits without sedation and without the use-limiting side effects that occur with propranolol.
Publication types
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Clinical Trial
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Controlled Clinical Trial
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Aged
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Aggression / drug effects*
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Aggression / psychology
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Clinical Trials as Topic
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Double-Blind Method
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Hospitalization
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Humans
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Impulsive Behavior / drug therapy*
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Impulsive Behavior / psychology
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Male
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Middle Aged
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Neurocognitive Disorders / drug therapy
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Neurocognitive Disorders / psychology*
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Pindolol / adverse effects
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Pindolol / pharmacology
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Pindolol / therapeutic use*
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Propranolol / adverse effects
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Rage / drug effects
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Sleep Stages
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Violence