Somat Cell Mol Genet. 1987 Nov;13(6):679-84.

Human gene coding for granulocyte-colony stimulating factor is assigned to the q21-q22 region of chromosome 17.

Kanda N, Fukushige S, Murotsu T, Yoshida MC, Tsuchiya M, Asano S, Kaziro Y, Nagata S.

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Tokyo Women's Medical College, Japan.

Abstract

Granulocyte-colony stimulating factor (G-CSF) is a member of colony stimulating factors which regulate the proliferation and differentiation of hematopoietic progenitor cells. A full-length cDNA clone coding human G-CSF was used as a hybridization probe to detect homologous sequence in human-mouse somatic cell hybrids, flow-sorted human chromosomes, and in situ human metaphase chromosomes. The results indicate that the gene encoding human G-CSF is on the q21-q22 region of chromosome 17, which is involved in translocation of t(15;17) (q23;21) in human acute promyelocytic leukemia.

PMID:: 3499671; [PubMed - indexed for MEDLINE]

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Cited by 2 PubMed Central articles

Fim-1, Fim-2/c-fms, and Fim-3, three common integration sites of Friend murine leukemia virus in myeloblastic leukemias, map to mouse chromosomes 13, 18, and 3, respectively. [J Virol. 1988]
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Sola B, Simon D, Mattéi MG, Fichelson S, Bordereaux D, Tambourin PE, Guenet JL, Gisselbrecht S. J Virol. 1988 Nov; 62(11):3973-8.
A StuI polymorphism in the human granulocyte colony-stimulating factor gene. [Nucleic Acids Res. 1989]
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Tani K, Asano S, Ozawa K, Takaku F. Nucleic Acids Res. 1989 Sep 25; 17(18):7544.

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Human gene coding for granulocyte-colony stimulating factor is assigned to the q...
Human gene coding for granulocyte-colony stimulating factor is assigned to the q21-q22 region of chromosome 17.
Somat Cell Mol Genet. 1987 Nov ;13(6):679-84.

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