Psychiatry Res. 1987 Aug;21(4):285-92.

Three subtypes of chronic schizophrenia identified using 11C-glucose positron emission tomography.

Kishimoto H, Kuwahara H, Ohno S, Takazu O, Hama Y, Sato C, Ishii T, Nomura Y, Fujita H, Miyauchi T, et al.

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Psychiatry Res 1988 Mar;23(3):353.

Abstract

The authors used positron computed tomography (CT) and 11C-labeled glucose to measure brain glucose utilization in 20 chronic schizophrenic patients (18 men, 2 women, mean age 38) and 5 male control subjects (mean age 38). Positron emission tomography (PET) revealed at least three subtypes: hypofrontal (type A), hypoparietal (right-sided disturbance in right-handed and left-sided disturbance in left-handed patients) (type B), and normal (type C). The significant count reduction in the frontal lobe (Brodmann's area 10) in type A patients was 38%, while that in the parietal lobe (Brodmann's area 40) in type B patients was 26% in each lobe of the brain.

PMID:: 3498177; [PubMed - indexed for MEDLINE]

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