Sepsis Due to Bloodstream Ralstonia mannitolilytica Infection After Surgical Treatment of Perianal Abscess: A Case Report

Jiamin Tu; Lei Tu; Yinping Jiang; Honghao Fu; Zijuan Mai; Xianglin Wu; Bing Xu

doi:10.2147/IDR.S329588

Sepsis Due to Bloodstream Ralstonia mannitolilytica Infection After Surgical Treatment of Perianal Abscess: A Case Report

Infect Drug Resist. 2021 Oct 27:14:4441-4445. doi: 10.2147/IDR.S329588. eCollection 2021.

Authors

Jiamin Tu¹, Lei Tu¹, Yinping Jiang², Honghao Fu¹, Zijuan Mai³, Xianglin Wu⁴, Bing Xu¹

Affiliations

¹ Department of Proctology, University of Chinese Academy of Science Shenzhen Hospital (GuangMing), Shenzhen, 518100, People's Republic of China.
² Department of Chinese Medicine, University of Chinese Academy of Science Shenzhen Hospital (GuangMing), Shenzhen, 518100, People's Republic of China.
³ Department of Medical Record Statistics Section, University of Chinese Academy of Science Shenzhen Hospital (GuangMing), Shenzhen, 518100, People's Republic of China.
⁴ Department of Laboratory, University of Chinese Academy of Science Shenzhen Hospital (GuangMing), Shenzhen, 518100, People's Republic of China.

Abstract

Background: Ralstonia mannitolilytica can cause opportunistic infections. Reports on this pathogen identified in the bloodstream are rare worldwide, especially in China.

Case description: We describe a 48-year-old man who developed sepsis due to bloodstream Ralstonia mannitolilytica infection after surgery for a perianal abscess. His condition deteriorated into multiple organ dysfunction syndromes until susceptible antibiotics (ceftriaxone and levofloxacin) were administrated based on the drug sensitivity test results. The patient had a satisfactory recovery with no complications during a 6-month follow-up period.

Conclusion: Ralstonia mannitolilytica blood-borne infection in patients evolves rapidly. The inconsistent sensitivity to antibiotics makes timely treatment difficult and can lead to serious complications. We report the clinical presentations and treatment outcomes for this patient here to remind clinicians about this rare opportunistic pathogen and to highlight the importance of bacterial culture, especially for immunocompromised patients.

Keywords: Ralstonia mannitolilytica; multiple organ dysfunction syndrome; perianal abscess; sepsis; shock.

Publication types

Case Reports

Grants and funding

This research was supported by the Project of Shenzhen Guangming District Science and Technology Innovation Commission (No. 2020R01122) and Guangming District Economic Development Special Fund, Shenzhen China (No. GM2019020013).