Platelet-Rich Plasma as a Potential New Strategy in the Endometrium Treatment in Assisted Reproductive Technology

Yunying Lin; Jia Qi; Yun Sun

doi:10.3389/fendo.2021.707584

Platelet-Rich Plasma as a Potential New Strategy in the Endometrium Treatment in Assisted Reproductive Technology

Front Endocrinol (Lausanne). 2021 Oct 18:12:707584. doi: 10.3389/fendo.2021.707584. eCollection 2021.

Authors

Yunying Lin^{1

2}, Jia Qi^{1

2}, Yun Sun^{1

2}

Affiliations

¹ Center for Reproductive Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
² Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai, China.

Abstract

The success rate of assisted reproduction techniques (ART) has long been less than satisfactory albeit the great progress made in recent years, demonstrating the need for alternative options in the ART cycles. Growing evidence correlates the effect of intrauterine platelet-rich plasma (PRP) infusion on the endometrium with reassuring reproductive results. Thus, in this review, we focus on the current clinical and mechanical evidence on PRP and its effect on endometrial receptivity, and assess the features, benefits and limitations of the current studies and potential risks of PRP in ART.

Keywords: assisted reproduction techniques; endometrial receptivity; mechanisms; platelet-rich plasma; risk.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Endometrium / drug effects*
Female
Humans
Infertility, Female / therapy*
Platelet-Rich Plasma / chemistry*
Pregnancy
Reproductive Techniques, Assisted / standards*