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    Cytogenet Cell Genet. 1986;41(1):38-41.

    Localization of the human haptoglobin genes distal to the fragile site at 16q22 using in situ hybridization.

    Simmers RN, Stupans I, Sutherland GR.

    The distamycin A-sensitive fragile site fra(16)(q22) is a precisely localized chromosomal marker. When expressed at metaphase, it visibly separates the chromosome material on either side of the fragile site. Using a cDNA probe encoding both the alpha and beta haptoglobin chains, the haptoglobin loci were found by in situ hybridization to be distal to fra(16)(q22).

    PMID: 3455911 [PubMed - indexed for MEDLINE]

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