Your browser version may not work well with NCBI's Web applications. More information here...
1: Postgrad Med J. 1987 Dec;63(746):1043-7.Click here to read Links

Congenital hypothyroidism from complete iodide transport defect: long-term evolution with iodide treatment.

Albero R, Cerdan A, Sanchez Franco F.

Servicio de Endocrinologia, C.S.S.S. La Paz, Madrid, Spain.

Hypothyroidism from iodide transport deficiency is a rare disease, especially when found in two affected siblings. Treatment with high doses of iodide has been recommended, but no long term results have been reported. Two siblings with congenital hypothyroidism due to total failure to transport iodide have been followed up during twelve and a half years of treatment with oral potassium iodide. Iodine doses varied between 10.3 and 22 mg/day, and serum total iodine concentrations between 100 and 210 micrograms/dl. Total triiodothyronine (T3), thyroxine (T4) and free T4 were in the normal range during the time of study. Basal thyroid stimulating hormones (TSH) and maximum TSH response to thyrotrophin releasing hormone (TRH) were also in the range of normal values. These data along with clinical findings confirmed the potential usefulness of iodine in hypothyroidism due to complete iodide transport defect.

PMID: 3451231 [PubMed - indexed for MEDLINE]

PMCID: PMC2428598

Patient Drug Information

  • Potassium (Glu-K® , K+ 10® , K+ 8® , ...)

    Potassium is essential for the proper functioning of the heart, kidneys, muscles, nerves, and digestive system. Usually the food you eat supplies all of the potassium you need. However, certain diseases (e.g., kidney dis...

  • Thyroid (Armour® Thyroid)

    Thyroid is a hormone produced by the body. When taken correctly, thyroid is used to treat the symptoms of hypothyroidism (a condition where the thyroid gland does not produce enough thyroid hormone). Symptoms of hypothyr...

  • Levothyroxine (Levothroid® , Levoxyl® , Synthroid® , ...)

    Levothyroxine, a thyroid hormone, is used to treat hypothyroidism, a condition where the thyroid gland does not produce enough thyroid hormone. Without this hormone, the body cannot function properly, resulting in poor g...

  • » See all 4 drug reports ...
  • Source: AHFS Consumer Medication Information