[Place of molecular imaging in the management of prostate cancer]

Cancer Radiother. 2021 Oct;25(6-7):663-666. doi: 10.1016/j.canrad.2021.07.032. Epub 2021 Aug 14.
[Article in French]

Abstract

In the management of prostate cancer in recent years, innovative therapies have appeared requiring precise and reliable disease detection. In 2021, new generation imaging (PET/CT, multiparametric MRI, PET/MRI) have their place at all stages of the prostate cancer natural history to help target the lesion(s) and guide therapy and improve the results obtained. PSMA PET/CT is currently the leader in this type of imaging with a complete offer during the disease: both from diagnosis, to recurrence or in the oligo-metastatic and metastatic stage resistant to castration with a pivotal role in the PSMA theranostic approach. However, multiparametric MRI also has many detection advantages when the prostate is left in place, which suggests the potential major benefit of hybrid PSMA PET/MRI imaging.

Keywords: Cancer de prostate; Imagerie de nouvelle génération; Initial staging; Next generation imaging; PET/CT; Prostate cancer; Recurrence; Récidive; Stadification; TEP/TDM.

Publication types

  • Review

MeSH terms

  • Antigens, Surface / blood
  • Bone Neoplasms / diagnostic imaging
  • Bone Neoplasms / secondary
  • Glutamate Carboxypeptidase II / blood
  • Humans
  • Magnetic Resonance Imaging / methods
  • Male
  • Molecular Imaging / methods*
  • Multimodal Imaging / methods*
  • Multiparametric Magnetic Resonance Imaging
  • Neoplasm Recurrence, Local / diagnostic imaging
  • Positron Emission Tomography Computed Tomography
  • Positron-Emission Tomography / methods
  • Prostatic Neoplasms / blood
  • Prostatic Neoplasms / diagnosis
  • Prostatic Neoplasms / diagnostic imaging*
  • Prostatic Neoplasms / pathology
  • Prostatic Neoplasms, Castration-Resistant / blood
  • Prostatic Neoplasms, Castration-Resistant / diagnostic imaging
  • Prostatic Neoplasms, Castration-Resistant / therapy

Substances

  • Antigens, Surface
  • FOLH1 protein, human
  • Glutamate Carboxypeptidase II