[Research progress on chemical constituents and pharmacological effects of Glycyrrhizae Radix et Rhizoma and discussion of Q-markers]

Zhongguo Zhong Yao Za Zhi. 2021 Jun;46(11):2660-2676. doi: 10.19540/j.cnki.cjcmm.20210304.201.
[Article in Chinese]

Abstract

Glycyrrhizae Radix et Rhizoma, a traditional Chinese herbal medicine, mainly contains triterpenoids, flavonoids, polysaccharides, coumarins and volatile oils with many pharmacological activities such as anti-tumor, anti-bacterial, anti-viral, anti-inflammatory, immune regulatory and anti-fibrotic effects. The widespread applications of Glycyrrhizae Radix et Rhizoma in food, medicine and chemical industries make its demand increase gradually. Therefore, the quality guarantee of the medicinal is of great value. Starting from the elaboration of chemical components and pharmacological effects of Glycyrrhizae Radix et Rhizoma and the introduction to the concept of quality marker(Q-marker), this study analyzed the Q-markers of Glycyrrhizae Radix et Rhizoma from the aspects of plant phylogene-tics, chemical component specificity, traditional efficacy, traditional medicinal properties, absorbed components, different processing methods and so on, which provides reference for quality evaluation, development and utilization of Glycyrrhizae Radix et Rhizoma.

Keywords: Glycyrrhizae Radix et Rhizoma; flavonoids; quality marker(Q-marker); quality standards; triterpenoid saponins.

MeSH terms

  • Drugs, Chinese Herbal* / pharmacology
  • Glycyrrhiza*
  • Rhizome
  • Triterpenes*

Substances

  • Drugs, Chinese Herbal
  • Triterpenes
  • glycyrrhizae radix et rhizoma