Organizing principles of the C. elegans contactome

Richard Betzel; Petra Vértes

doi:10.1016/j.cels.2021.06.004

Organizing principles of the C. elegans contactome

Cell Syst. 2021 Jul 21;12(7):689-691. doi: 10.1016/j.cels.2021.06.004.

Authors

Richard Betzel¹, Petra Vértes²

Affiliations

¹ Department of Psychological and Brain Sciences, Indiana University, Bloomington, IN 47405, USA; Cognitive Science Program, Indiana University, Bloomington, IN 47405, USA; Program in Neuroscience, Indiana University, Bloomington, IN 47405, USA; Network Science Institute, Indiana University, Bloomington, IN 47405, USA. Electronic address: rbetzel@indiana.edu.
² Department of Psychiatry, University of Cambridge, Cambridge CB2 0SZ, UK; The Alan Turing Institute, London SE5 8AF, UK. Electronic address: pv226@cam.ac.uk.

PMID: 34293322
DOI: 10.1016/j.cels.2021.06.004

Abstract

Two recent studies published in Nature generate and analyze, for the first time, the network of ∼100,000 membrane contacts between neurons in the C. elegans nerve ring. These novel data, extracted from legacy electron microscographs, represent a shift in our understanding of C. elegans neural networks and their similarity to mammalian brains.

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MeSH terms

Animals
Brain
Caenorhabditis elegans*
Neural Networks, Computer*
Neurons