Peripheral Ulcerative Keratitis Associated With Large Vessel Vasculitis

Shun Uchida; Yuki Kaji; Mutushito Ui; Hirotoshi Kawashima; Tomohiko Usui; Yoshiyuki Ohira

doi:10.7759/cureus.15767

Peripheral Ulcerative Keratitis Associated With Large Vessel Vasculitis

Cureus. 2021 Jun 20;13(6):e15767. doi: 10.7759/cureus.15767. eCollection 2021 Jun.

Authors

Shun Uchida¹, Yuki Kaji¹, Mutushito Ui¹, Hirotoshi Kawashima², Tomohiko Usui³, Yoshiyuki Ohira¹

Affiliations

¹ General Medicine, International University of Health and Welfare Narita Hospital, Chiba, JPN.
² Allergy and Rheumatology, International University of Health and Welfare Narita Hospital, Chiba, JPN.
³ Ophthalmology, International University of Health and Welfare Narita Hospital, Chiba, JPN.

Abstract

Peripheral ulcerative keratitis (PUK) is a non-infectious ulcer at the peripheral corneal stroma. Autoimmune diseases can cause PUK, but PUK caused by large vessel vasculitis (LVV) has rarely been reported. We report the case of a 71-year-old woman with complaints of low-grade fever and left eye pain. Ophthalmologic examination revealed PUK in the left eye, and we diagnosed LVV by ¹⁸F-fluorodeoxyglucose-positron emission tomography (FDG-PET) findings. The patient was treated with topical betamethasone eye drops for PUK and oral prednisolone for LVV. This case suggests that LVV can cause PUK.

Keywords: 18fdg-pet; episcleritis; giant cell arteritis; large vessel vasculitis; peripheral ulcerative keratitis.

Publication types

Case Reports