Format

Send to:

Choose Destination
See comment in PubMed Commons below
Genetics. 1987 Dec;117(4):777-82.

Autocorrelation of gene frequencies under isolation by distance.

Author information

  • 1Department of Ecology and Evolution, State University of New York, Stony Brook 11794.

Abstract

Spatial autocorrelation statistics are used for description of geographic variation of gene frequencies, but the relationship of these indices with the parameters describing the genetic structure of populations is not established. A simple relation is derived here between kinship coefficient and a measure of spatial autocorrelation, Moran's I. The autocorrelation coefficient of gene frequencies at a given distance is a direct function of the kinship at that distance, and an inverse function of the standardized gene frequency variance, Fst. Under isolation by distance, the expected values of Moran's I for any allele may be calculated by means of Mal├ęcot-Morton function, which predicts an exponential decline of genetic similarity in space. This allows comparison of observed gene frequency patterns with the patterns that should be caused by interaction of short range migration and random genetic drift.

PMID:
3428574
[PubMed - indexed for MEDLINE]
PMCID:
PMC1203249
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire Icon for PubMed Central
    Loading ...
    Write to the Help Desk