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Experientia. 1988 Sep 15;44(9):762-4.

Enantiomeric cannabinoids: stereospecificity of psychotropic activity.

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  • 1Brettler Medical Research Center, Faculty of Medicine, Hebrew University, Jerusalem, Israel.

Abstract

The 1,1-dimethylheptyl homolog of (-)-(3R,4R)-7-hydroxy-delta-6- tetrahydrocannabinol (compound II) is highly psychotropic in mice, rats and pigeons. The (+)-(3S,4S) enantiomer (III) was found to be psychotropically inactive at doses up to several thousand times those of the ED50 of (II).

PMID:
3416993
[PubMed - indexed for MEDLINE]
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