Experientia. 1988 Sep 15;44(9):762-4.

Enantiomeric cannabinoids: stereospecificity of psychotropic activity.

Mechoulam R, Feigenbaum JJ, Lander N, Segal M, Järbe TU, Hiltunen AJ, Consroe P.

Source

Brettler Medical Research Center, Faculty of Medicine, Hebrew University, Jerusalem, Israel.

Abstract

The 1,1-dimethylheptyl homolog of (-)-(3R,4R)-7-hydroxy-delta-6- tetrahydrocannabinol (compound II) is highly psychotropic in mice, rats and pigeons. The (+)-(3S,4S) enantiomer (III) was found to be psychotropically inactive at doses up to several thousand times those of the ED50 of (II).

PMID:: 3416993; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances, Grant Support

Publication Types

MeSH Terms

Substances

Cannabinoids

Grant Support

NS 15441/NS/NINDS NIH HHS/United States

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Experientia. 1988 Sep 15 ;44(9):762-4.

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