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    Neurology. 1988 Sep;38(9):1478-80.

    The treatment of Friedreich's ataxia with amantadine hydrochloride.

    Source

    Department of Neurology, Wayne State University, Detroit, MI.

    Abstract

    Amantadine hydrochloride (AH) was orally administered to 16 patients with Friedreich's ataxia. We evaluated patient response with the functional ataxia scoring scale and calculated a total disability score. The mean percent improvement of the total disability score was 29.5%; for ambulatory patients alone it was 45.5%. No significant side effects were encountered. AH appears to be a safe and effective symptomatic treatment of Friedreich's ataxia.

    PMID:
    3412597
    [PubMed - indexed for MEDLINE]

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