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Somat Cell Mol Genet. 1988 Jul;14(4):411-4.

Gene for lipoamide dehydrogenase maps to human chromosome 7.

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  • 1Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada.


The gene for lipoamide dehydrogenase (LD) has been assigned to human chromosome 7 based on filter hybridization analysis of genomic DNA from rodent-human somatic cell hybrids using a cDNA probe for human LD. No indication of multiple copies of the gene was found, in accordance with previous evidence that LD in the pyruvate, alpha-ketoglutarate, and branched chain alpha-ketoacid dehydrogenase complexes is genetically as well as biochemically identical.

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