West J Med. 1977 Dec;127(6):455-60.

Creatine phosphokinase-MB (CPK-MB) and the diagnosis of myocardial infarction.

Abstract

Creatine phosphokinase-MB (CPK-MB) is the most sensitive and the most specific indicator available for the diagnosis of an acute myocardial infarction. With the exception of after-cardiac surgical procedures, the degree and the duration of CPK-MB elevation in serum approximates the extent of an acute myocardial infarction, although a variety of factors may affect the reliability of such an index. Differences in the fractionation and assay methods for the creatine phosphokinase isoenzymes have produced conflicting documentation as to the presence of CPK-MB in tissues other than myocardium and the release of CPK-MB under conditions other than an acute myocardial infarction. The embryological development of the CPK-MB isoenzymes, as well as the various conditions involving increased CPK-BB serum activity, also deserve attention.

PMID:: 339548; [PubMed - indexed for MEDLINE]
PMCID:: PMC1237914

Free PMC Article

Publication Types, MeSH Terms, Substances

Publication Types

Review

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Other Literature Sources

Labome Researcher Resource - ExactAntigen/Labome

Medical

Heart Attack - MedlinePlus Health Information

Supplemental Content

Save items

Related citations in PubMed

Specificity of elevated serum MB creatine phosphokinase activity in the diagnosis of acute myocardial infarction. [Am J Cardiol. 1975]
Specificity of elevated serum MB creatine phosphokinase activity in the diagnosis of acute myocardial infarction.
Roberts R, Gowda KS, Ludbrook PA, Sobel BE. Am J Cardiol. 1975 Oct 6; 36(4):433-7.
Elevated plasma MB creatine phosphokinase activity. A specific marker for myocardial infarction in perioperative patients. [Arch Intern Med. 1976]
Elevated plasma MB creatine phosphokinase activity. A specific marker for myocardial infarction in perioperative patients.
Roberts R, Sobel BE. Arch Intern Med. 1976 Apr; 136(4):421-4.
Cardiac specific creatine phosphokinase isoenzyme in the diagnosis of acute myocardial infarction. [Circulation. 1975]
Cardiac specific creatine phosphokinase isoenzyme in the diagnosis of acute myocardial infarction.
Varat MA, Mercer DW. Circulation. 1975 May; 51(5):855-9.
Review Diagnosis of myocardial infarction by serum isoenzyme analysis. [Ann Clin Lab Sci. 1977]
Review Diagnosis of myocardial infarction by serum isoenzyme analysis.
Roe CR. Ann Clin Lab Sci. 1977 May-Jun; 7(3):201-9.
Review Creatine kinase MB isoenzyme in the evaluation of myocardial infarction. [Curr Probl Cardiol. 1979]
Review Creatine kinase MB isoenzyme in the evaluation of myocardial infarction.
Navin TR, Hager WD. Curr Probl Cardiol. 1979 Mar; 3(12):1-32.

See reviews... See all...

Cited by 1 PubMed Central article

Cardiovascular complications during prolonged starvation. [West J Med. 1979]
Cardiovascular complications during prolonged starvation.
Rose M, Greene RM. West J Med. 1979 Feb; 130(2):170-7.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound
PubChem chemical compound records that cite the current articles. These references are taken from those provided on submitted PubChem chemical substance records. Multiple substance records may contribute to the PubChem compound record.
References for this PMC Article
Citation referenced in PubMed article. Only valid for PubMed citations that are also in PMC.
Substance
PubChem chemical substance records that cite the current articles. These references are taken from those provided on submitted PubChem chemical substance records.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Free in PMC
Free full text articles in PMC
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Creatine phosphokinase-MB (CPK-MB) and the diagnosis of myocardial infarction.
Creatine phosphokinase-MB (CPK-MB) and the diagnosis of myocardial infarction.
West J Med. 1977 Dec ;127(6):455-60.

PubMed
Reciprocal effects of hormonal fluctuations on human motor and perceptual-spatia...
Reciprocal effects of hormonal fluctuations on human motor and perceptual-spatial skills.
Behav Neurosci. 1988 Jun ;102(3):456-9.

PubMed
Purification and characterization of unique glutathione S-transferases from huma...
Purification and characterization of unique glutathione S-transferases from human muscle.
Arch Biochem Biophys. 1988 Jul ;264(1):13-22.

PubMed
A case of organic brain syndrome following head injury successfully treated with...
A case of organic brain syndrome following head injury successfully treated with carbamazepine.
Acta Psychiatr Scand. 1988 Mar ;77(3):361-3.

PubMed
Acid-base curve nomogram for chimpanzee blood and comparison with human blood ch...
Acid-base curve nomogram for chimpanzee blood and comparison with human blood characteristics.
J Appl Physiol. 1979 Feb ;46(2):381-6.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: