Near-Complete Genome Sequences of Eight Human Astroviruses Recovered from Diarrheal Stool Samples of Hospitalized Children in Coastal Kenya in 2019

Arnold W Lambisia; My V T Phan; Zaydah R de Laurent; Matthew Cotten; D James Nokes; Charles N Agoti

doi:10.1128/MRA.00162-21

Near-Complete Genome Sequences of Eight Human Astroviruses Recovered from Diarrheal Stool Samples of Hospitalized Children in Coastal Kenya in 2019

Microbiol Resour Announc. 2021 Apr 15;10(15):e00162-21. doi: 10.1128/MRA.00162-21.

Authors

Arnold W Lambisia¹, My V T Phan², Zaydah R de Laurent³, Matthew Cotten², D James Nokes^{3

4}, Charles N Agoti^{3

5}

Affiliations

¹ Kenya Medical Research Institute (KEMRI)-Wellcome Trust Research Programme, Centre for Geographic Medicine Research-Coast, Kilifi, Kenya alambisia@kemri-wellcome.org.
² UK Medical Research Council, Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine Uganda Research Unit, Entebbe, Uganda.
³ Kenya Medical Research Institute (KEMRI)-Wellcome Trust Research Programme, Centre for Geographic Medicine Research-Coast, Kilifi, Kenya.
⁴ School of Life Sciences and Zeeman Institute (SBIDER), University of Warwick, Coventry, United Kingdom.
⁵ School of Health and Human Sciences, Pwani University, Kilifi, Kenya.

Abstract

Here, using a sequence-independent sequencing approach (M. V. Phan, P. Hong Anh, N. Van Cuong, B. Oude Munnink, et al., Virus Evol 2:vew027, 2016, https://doi.org/10.1093/ve/vew027), we determined human astrovirus (HAstV) genome sequences from eight diarrheal stool samples collected in coastal Kenya in 2019. Phylogenetic analysis identified the following 4 genotypes: HAstV-1 (n = 4), HAstV-2 (n = 1), HAstV-3 (n = 1), and HAstV-5 (n = 2).

Grants and funding

MC_UU_12014/12/MRC_/Medical Research Council/United Kingdom