Investigation of Clostridium difficile in elderly people: A preliminary study in Iran

Trop Doct. 2021 Jul;51(3):319-322. doi: 10.1177/0049475521999221. Epub 2021 Apr 13.

Abstract

Elderly people are at increased risk for infections such as with Clostridium difficile. This can colonize their gut and cause various gastro-intestinal manifestations. Our survey investigated its prevalence in a nursing home in Iran. Faecal samples were collected and tested by polymerase chain reaction for identification of A, B and binary toxin genes. From 289 samples, 42(14.5%) isolates were found. Toxin genes were positive in 19 isolates (17 AþBþ and 2 isolates ABþ). The elderly are especially at risk and great attention should be paid to contamination within their nursing homes. This is not an isolated regional problem.

Keywords: Clostridium difficile; Iran; elderly; toxin.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Clostridioides difficile / genetics
  • Clostridioides difficile / isolation & purification*
  • Clostridium Infections / diagnosis*
  • Clostridium Infections / epidemiology
  • Feces / microbiology
  • Female
  • Humans
  • Iran / epidemiology
  • Male
  • Middle Aged
  • Nursing Homes
  • Polymerase Chain Reaction