Viral epidemiology and SARS-CoV-2 co-infections with other respiratory viruses during the first COVID-19 wave in Paris, France

Influenza Other Respir Viruses. 2021 Jul;15(4):425-428. doi: 10.1111/irv.12853. Epub 2021 Apr 4.

Abstract

Objectives: Our work assessed the prevalence of co-infections in patients with SARS-CoV-2.

Methods: All patients hospitalized in a Parisian hospital during the first wave of COVID-19 were tested by multiplex PCR if they presented ILI symptoms.

Results: A total of 806 patients (21%) were positive for SARS-CoV-2, 755 (20%) were positive for other respiratory viruses. Among the SARS-CoV-2-positive patients, 49 (6%) had viral co-infections. They presented similar age, symptoms, except for fever (P = .013) and headaches (P = .048), than single SARS-CoV-2 infections.

Conclusions: SARS-CoV-2-infected patients presenting viral co-infections had similar clinical characteristics and prognosis than patients solely infected with SARS-CoV-2.

Keywords: SARS-CoV-2; respiratory viruses; syndromic testing; viral co-infection.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • COVID-19 / diagnosis
  • COVID-19 / epidemiology
  • Coinfection / diagnosis
  • Coinfection / epidemiology*
  • Female
  • Hospitalization
  • Humans
  • Male
  • Middle Aged
  • Multiplex Polymerase Chain Reaction
  • Paris / epidemiology
  • Prevalence
  • Prognosis
  • Respiratory Tract Infections / diagnosis
  • Respiratory Tract Infections / epidemiology*
  • SARS-CoV-2 / genetics
  • SARS-CoV-2 / isolation & purification
  • Virus Diseases / diagnosis
  • Virus Diseases / epidemiology*
  • Viruses / classification
  • Viruses / genetics
  • Viruses / isolation & purification