Investigation of Structural, Treatment, and Clinical Characteristics of COVID-19 Along with the Challenges Caused by its Prevalence

Maham Doagooyan; Seyedeh Hoda Alavizadeh; Javad Akhtari; Amirhossein Sahebkar; Saeed Ghanbari Hasan Kiade; Pariya Haghgoo Kochesfahani; Fatemeh Gheybi

doi:10.2174/1871526521666210322160038

Investigation of Structural, Treatment, and Clinical Characteristics of COVID-19 Along with the Challenges Caused by its Prevalence

Infect Disord Drug Targets. 2022;22(1):e220321192415. doi: 10.2174/1871526521666210322160038.

Authors

Maham Doagooyan¹, Seyedeh Hoda Alavizadeh^{2

3}, Javad Akhtari^{4

5}, Amirhossein Sahebkar^{6

7

8}, Saeed Ghanbari Hasan Kiade⁹, Pariya Haghgoo Kochesfahani¹⁰, Fatemeh Gheybi¹

Affiliations

¹ Department of Medical Biotechnology and Nanotechnology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
² Nanotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.
³ Department of Pharmaceutical Nanotechnology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.
⁴ Department of Medical Nanotechnology, School of Advanced Technologies in Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
⁵ Toxoplasmosis Research Center, Communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran.
⁶ Halal Research Center of IRI, FDA, Tehran, Iran.
⁷ Neurogenic Inflammation Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
⁸ Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.
⁹ Biotechnology Faculty, Amol University of Special Modern Technologies, Amol, Iran.
¹⁰ Engineering Faculty, Islamic Azad University Central Tehran Branch, Tehran, Iran.

PMID: 33749564
DOI: 10.2174/1871526521666210322160038

Abstract

In late 2019, a report from China was published stating a disease with an unknown cause. After that, the outbreak of the COVID-19 caused a pandemic in the world. On March 11, 2020, the outbreak of this virus was reported in 100 countries. The virus is currently spreading rapidly around the world. In the past, coronaviruses caused lifethreatening diseases such as SARS and MERS in some areas of the world. Although there is still a debate about the origin of this new coronavirus, it is most likely linked with some animals, including bats, civet, and pangolin. In this review, we try to describe the features of the new coronavirus as well as the recent diagnostic and therapeutic findings.

Keywords: COVID-19; SARS-CoV-2; coronavirus; diagnosis; pandemic; treatment.

Publication types

Review

MeSH terms

Animals
COVID-19* / epidemiology
Chiroptera*
Humans
Middle East Respiratory Syndrome Coronavirus*
Pandemics
Prevalence
SARS-CoV-2