Abstract
The prognosis of central nervous system infections caused by enteroviruses partially depends on the viral genotype, which is not provided by current point-of-care diagnostic methods. In this study, next-generation sequencing identified an echovirus 9 directly from the cerebrospinal fluid of a patient presenting with meningitis.
Keywords:
Echovirus; Enterovirus; Genotype; Next-generation sequencing; Point-of-care diagnosis; meningitis.
© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
MeSH terms
-
Adult
-
Central Nervous System Infections / diagnosis*
-
Central Nervous System Infections / epidemiology
-
Central Nervous System Infections / virology
-
Echovirus 9 / classification
-
Echovirus 9 / genetics*
-
Echovirus 9 / pathogenicity
-
Echovirus Infections / cerebrospinal fluid
-
Echovirus Infections / diagnosis*
-
Echovirus Infections / epidemiology*
-
Female
-
France / epidemiology
-
Genotype*
-
High-Throughput Nucleotide Sequencing / methods*
-
Humans
-
Meningitis, Viral / diagnosis*
-
Meningitis, Viral / epidemiology
-
Meningitis, Viral / virology
-
Phylogeny
-
RNA, Viral / genetics
-
Whole Genome Sequencing