Successful Bronchoscopic Treatment for Postoperative Bronchopleural Fistula Using N-butyl-2-cyanoacrylate (NBCA): Report of a Post-completion Pneumonectomy Case with a History of Induction Chemoradiotherapy Followed by Bilobectomy for Advanced Lung Cancer

Acta Med Okayama. 2021 Feb;75(1):91-94. doi: 10.18926/AMO/61440.

Abstract

Bronchopleural fistula (BPF) is a severe complication following lung resection. We present the case of a patient with a history of advanced lung cancer, who had undergone induction chemoradiotherapy followed by right middle and lower lobectomy, and who developed BPF after completion right pneumonectomy. Although we had covered the bronchial stump with an omental pedicled flap, BPF was found on postoperative day 19. We covered the fistula with n-butyl-2-cyanoacrylate (NBCA) using bronchoscopy. Although we had to repeat the NBCA treatment, we ultimately cured the patient's BPF and no recurrence was observed up to 15.2 months after surgery.

Keywords: bronchopleural fistula; induction chemoradiotherapy; n-butyl-2-cyanoacrylate (NBCA); omental pedicled flap; pneumonectomy.

Publication types

  • Case Reports

MeSH terms

  • Bronchial Fistula / diagnostic imaging
  • Bronchial Fistula / etiology
  • Bronchial Fistula / therapy*
  • Bronchoscopy
  • Chemoradiotherapy, Adjuvant / adverse effects
  • Enbucrilate / therapeutic use*
  • Humans
  • Lung Neoplasms / therapy
  • Male
  • Middle Aged
  • Pneumonectomy / adverse effects*
  • Postoperative Complications / drug therapy
  • Postoperative Complications / etiology

Substances

  • Enbucrilate