Uptake kinetics and accumulation of pesticides in wheat (Triticum aestivum L.): Impact of chemical and plant properties

Plant uptake is an important process in determining the transfer of pesticides through a food chain. Understanding how crops take up and translocate pesticides is critical in developing powerful models to predict pesticide accumulation in agricultural produce and potential human exposure. Herein, wheat was selected as a model plant species to investigate the uptake and distribution of eleven widely used pesticides in a hydroponic system as a function of time for 144 h. The time-dependent uptake kinetics of these pesticides were fitted with a first-order 1-compartment kinetic model. During 144 h, flusilazole and difenoconazole, with relative high log K_ow (3.87 and 4.36, respectively), displayed higher root uptake rate constants (k). To clarify the role of root lipid content (f_lip) in plant accumulation of pesticides, we conducted a lipid normalization meta-analysis using data from this and previous studies, and found that the f_lip value was an important factor in predicting the root concentration factor (RCF) of pesticides. An improved correlation was observed between log RCF and log f_lipK_ow (R² = 0.748, N = 26, P < 0.001), compared with the correlation between log RCF and log K_ow (R² = 0.686, N = 26, P < 0.001). Furthermore, the hydrophilic pesticides (e.g. log K_ow < 2) were found to reach partition equilibrium faster than lipophilic pesticides (e.g. log K_ow > 3) during the uptake process. The quasi-equilibrium factor (α_pt) was inversely related to log K_ow (R² = 0.773, N = 11, P < 0.001) suggesting a hydrophobicity-regulated uptake equilibrium. Findings from this study could facilitate crop-uptake model optimization.