Comparison of lung ultrasound and other volumetric methods in peritoneal dialysis patients

Medicine (Baltimore). 2021 Jan 22;100(3):e23856. doi: 10.1097/MD.0000000000023856.

Abstract

Although many alternative methods are present, maintaining ideal volume status in peritoneal dialysis (PD) patients still rely on clinical evaluation due to lack of an evidence-based method. Lung ultrasound (LUS) is a new method for evaluation of hidden congestion in this group.LUS findings and its relationship with other volumetric methods are investigated in this observational cross-sectional study.In this observational cross sectional study, LUS was performed to all PD patients and compared with symptoms of hypervolemia, physical examination, vascular endothelial growth factor-C (VEGF-C), and N-terminal pro-brain natriuretic peptide levels, chest radiography, echocardiography, bioelectrical impedance analysis.Data of 21 PD patients were evaluated. There was correlation between number of B lines and VEGF-C levels (r = 0.447, P = .042), daily urine output (r = 0.582, P = .007) and left ventricle mass index (r = -0.456, P = .038). Correlations with all other parameters were not significant. Daily urine output and VEGF-C levels were significantly different when B lines were grouped into 2 according to the median level (P < .05 for all).This is the widest spectrum study looking for LUS findings and other volumetric parameters in a small PD cohort. LUS might be useful to evaluate hidden hypervolemia. Its correlation with VEGF-C level is a novel finding.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Cohort Studies
  • Cross-Sectional Studies
  • Echocardiography
  • Female
  • Humans
  • Male
  • Middle Aged
  • Peritoneal Dialysis*
  • Pulmonary Edema / blood
  • Pulmonary Edema / diagnostic imaging*
  • Ultrasonography
  • Vascular Endothelial Growth Factor C / blood

Substances

  • Vascular Endothelial Growth Factor C