FEBS Lett. 1988 Feb 8;228(1):89-93.

5-Aminolevulinic acid formation from glutamate via the C5 pathway in Clostridium thermoaceticum.

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Department of Chemistry, Texas A&M University, College Station 77843.

Abstract

A cell-free extract of the anaerobic eubacterium, Clostridium thermoaceticum, catalyzes the synthesis of 5-aminolevulinic acid (ALA) from glutamate via the C5 pathway. The enzyme reaction resembles that of higher plants and algae in cofactor requirements and sensitivity to ribonuclease. From the phylogenetic distribution it is proposed that the C5 pathway evolved earlier than the ALA synthase pathway.

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Characterization of the process of 5-aminolevulinic acid formation from glutamate via the C5 pathway in Clostridium thermoaceticum. [Int J Biochem. 1991]
Characterization of the process of 5-aminolevulinic acid formation from glutamate via the C5 pathway in Clostridium thermoaceticum.
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Cited by 7 PubMed Central articles

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