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Br J Dermatol. 1988 Jan;118(1):41-6.

Lichen sclerosus et atrophicus and autoimmunity--a study of 350 women.

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  • 1Department of Dermatology, St Bartholomew's Hospital, West Smithfield, London, UK.

Erratum in

  • Br J Dermatol 1988 May;118(5):736.


A study of autoimmune related phenomena in 350 women with histologically confirmed lichen sclerosus et atrophicus revealed that 21.5% had one or more autoimmune related diseases, 21% had one or more first degree relatives with an autoimmune-related disease, 42% had an autoantibody at a titre greater than 1:20, and 59.5% had one or more of these autoimmune-related phenomena. No statistically significant differences in the natural history of lichen sclerosus et atrophicus were demonstrated between those patients with autoimmune-related phenomena and those without.

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