Invasive Scopulariopsis in the immunocompromised host

Am J Med. 1987 Dec;83(6):1163-6. doi: 10.1016/0002-9343(87)90961-2.

Abstract

Opportunistic infections with fungal organisms have been well described in patients undergoing intensive chemotherapy and bone marrow transplantation. In two patients, invasive infections with the saprophyte Scopulariopsis developed either following intensive chemotherapy or bone marrow transplant. Fungal disease persisted in both patients despite resection of the primary focus and prolonged treatment with the usual antifungal agents, and contributed to the death of one patient.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Acute Disease
  • Adolescent
  • Adult
  • Amphotericin B / therapeutic use
  • Bone Marrow Transplantation*
  • Humans
  • Immune Tolerance*
  • Leukemia / complications*
  • Leukemia / therapy
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive / complications*
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive / therapy
  • Male
  • Mitosporic Fungi
  • Mycoses / complications*
  • Mycoses / prevention & control
  • Opportunistic Infections / complications*
  • Opportunistic Infections / prevention & control
  • Remission Induction

Substances

  • Amphotericin B