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Am J Med Genet. 1987 Nov;28(3):655-9.

Familial ossicular malformations: case report and review of literature.

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  • 1Department of Otolaryngology, School of Medicine, Akita University, Japan.

Abstract

Familial middle ear ossicular anomalies are rare. We report on a daughter and her mother with congenital conductive hearing loss. Tympanotomy disclosed hypoplasia of long crus of incus whose tip had been replaced with a fibrous strand. A review suggests that middle ear ossicular anomalies may be inherited as autosomal dominant traits. Most individuals were bilaterally affected. Most isolated cases were affected unilaterally.

PMID:
3322009
[PubMed - indexed for MEDLINE]
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