Cancer Detect Prev Suppl. 1987;1:373-6.

Transfer factor for adjuvant immunotherapy in cervical cancer.

Wagner G, Knapp W, Gitsch E, Selander S.

Source

1st Department of Obstetrics and Gynecology, University of Vienna, Austria.

Abstract

In a prospective randomized double-blind study of 60 patients with invasive cervical cancer, 32 were treated with transfer factor (TF) derived from leukocytes of the patients' husbands, and 28 were treated with placebo. Within the first 2 years after radical hysterectomy, five out of 32 TF-treated patients and 11 out of 28 placebo-treated patients developed recurrence of malignancy. Excluding one further patient with intercurrent death this difference is significant (chi 2 = 3.9915; P less than 0.05). Subdividing the collectives, significant differences were found in patients aged below 35 years and in patients with stage I disease. Identical immune profiles were checked in leukocyte donors prior to leukophoresis and were serially checked in patients. Antigen-specific correlations were found between donors' and recipients' reactivities but not between donors' reactivity and recipient's course of the disease.

PMID:: 3319147; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

Transfer Factor

LinkOut - more resources

Medical

Supplemental Content

Save items

Related citations in PubMed

[Transfer factor as adjuvant immunotherapy in invasive cervix cancer. Report of a double-blind study]. [Wien Klin Wochenschr. 1983]
[Transfer factor as adjuvant immunotherapy in invasive cervix cancer. Report of a double-blind study].
Wagner G, Gitsch E, Havelec L, Knapp W, Rainer H, Selander S. Wien Klin Wochenschr. 1983 Oct 28; 95(20):738-42.
Review Clinical trials of transfer factor in malignancy. [J Exp Pathol. 1987]
Review Clinical trials of transfer factor in malignancy.
Spitler LE, Miller L. J Exp Pathol. 1987 Summer; 3(4):549-64.
Cooperative trial of immunotherapy for nasopharyngeal carcinoma with transfer factor from donors with Epstein-Barr virus antibody activity. [Cancer Treat Rep. 1985]
Cooperative trial of immunotherapy for nasopharyngeal carcinoma with transfer factor from donors with Epstein-Barr virus antibody activity.
Goldenberg GJ, Brandes LJ, Lau WH, Miller AB, Wall C, Ho JH. Cancer Treat Rep. 1985 Jul-Aug; 69(7-8):761-7.
A randomized, double-blind, placebo-controlled trial of transfer factor as adjuvant therapy for malignant melanoma. [Cancer. 1988]
A randomized, double-blind, placebo-controlled trial of transfer factor as adjuvant therapy for malignant melanoma.
Miller LL, Spitler LE, Allen RE, Minor DR. Cancer. 1988 Apr 15; 61(8):1543-9.
Review Immunotherapy of superficial bladder cancer. [J Urol. 1982]
Review Immunotherapy of superficial bladder cancer.
Shapiro A, Kadmon D, Catalona WJ, Ratliff TL. J Urol. 1982 Nov; 128(5):891-4.

See reviews... See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.

Recent activity

Clear Turn Off Turn On

Transfer factor for adjuvant immunotherapy in cervical cancer.
Transfer factor for adjuvant immunotherapy in cervical cancer.
Cancer Detect Prev Suppl. 1987 ;1:373-6.

PubMed
Laminin expression in colorectal carcinomas varying in degree of differentiation...
Laminin expression in colorectal carcinomas varying in degree of differentiation.
Arch Surg. 1987 Dec ;122(12):1470-4.

PubMed
An evaluation of family therapy in anorexia nervosa and bulimia nervosa.
An evaluation of family therapy in anorexia nervosa and bulimia nervosa.
Arch Gen Psychiatry. 1987 Dec ;44(12):1047-56.

PubMed
[Adenomatous polyps with prostatic type epithelium: a report of two cases].
[Adenomatous polyps with prostatic type epithelium: a report of two cases].
Hinyokika Kiyo. 1987 Jul ;33(7):1132-8.

PubMed
Mortality and morbidity from malaria among children in a rural area of The Gambi...
Mortality and morbidity from malaria among children in a rural area of The Gambia, West Africa.
Trans R Soc Trop Med Hyg. 1987 ;81(3):478-86.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: