Epidemiology of COVID-19 and Predictors of Outcome in Nigeria: A Single-Center Study

Am J Trop Med Hyg. 2020 Dec;103(6):2376-2381. doi: 10.4269/ajtmh.20-0759. Epub 2020 Oct 26.

Abstract

There is a paucity of information regarding the epidemiology and outcome of COVID-19 from low/middle-income countries, including from Nigeria. This single-center study described the clinical features, laboratory findings, and predictors of in-hospital mortality of COVID-19 patients. Patients admitted between April 10, 2020 and June 10, 2020 were included. Forty-five patients with a mean age of 43 (16) years, predominantly male (87%), presented with fever (38%), cough (29%), or dyspnea (24%). In-hospital mortality was 16%. The independent predictors of mortality were hypoxemia (adjusted odds ratio [aOR]: 2.5; 95% CI: 1.3-5.1) and creatinine > 1.5 mg/dL (aOR: 4.3; 95% CI: 1.9-9.8).

MeSH terms

  • Adult
  • Aged
  • Asymptomatic Diseases
  • COVID-19 / diagnosis
  • COVID-19 / epidemiology*
  • COVID-19 / mortality*
  • Cough / diagnosis
  • Cough / physiopathology
  • Cough / virology
  • Creatinine / blood
  • Dyspnea / diagnosis
  • Dyspnea / physiopathology
  • Dyspnea / virology
  • Female
  • Fever / diagnosis
  • Fever / physiopathology
  • Fever / virology
  • Hospital Mortality / trends*
  • Hospitalization / statistics & numerical data
  • Humans
  • Hypoxia / diagnosis
  • Hypoxia / physiopathology
  • Male
  • Middle Aged
  • Nigeria / epidemiology
  • Pandemics*
  • Prognosis
  • Retrospective Studies
  • Risk Factors
  • SARS-CoV-2 / pathogenicity*
  • Severity of Illness Index
  • Tertiary Care Centers

Substances

  • Creatinine