Sex and gender differences in axial spondyloarthritis: myths and truths

Rheumatology (Oxford). 2020 Oct 1;59(Suppl4):iv38-iv46. doi: 10.1093/rheumatology/keaa543.

Abstract

Mounting evidence reveals evident sex differences in physiology, disease presentation and response to medication in axial SpA (axSpA). Unfortunately these data are often neglected in clinical practice and research. In this review, myths that still exist on diagnosis, disease manifestation and drug effectiveness were argued against data of the most recent literature. The aim is to increase awareness of sex differences in the clinical aspects of axSpA.

Keywords: biological therapies; epidemiology; inflammation; patient reported outcomes; sex differences; spondyloarthritis.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Anti-Inflammatory Agents / therapeutic use
  • Disease Progression
  • Female
  • Humans
  • Male
  • Risk Factors
  • Sex Factors
  • Spondylarthritis / diagnosis*
  • Spondylarthritis / drug therapy
  • Spondylarthritis / etiology
  • Spondylarthritis / pathology
  • Treatment Outcome

Substances

  • Anti-Inflammatory Agents