Angiotensin-converting enzyme 2 expression is not induced by the renin-angiotensin system in the lung

Ryuta Baba; Kenji Oki; Kiyotaka Itcho; Kazuhiro Kobuke; Gaku Nagano; Haruya Ohno; Masayasu Yoneda; Noboru Hattori

doi:10.1183/23120541.00402-2020

Angiotensin-converting enzyme 2 expression is not induced by the renin-angiotensin system in the lung

ERJ Open Res. 2020 Oct 5;6(4):00402-2020. doi: 10.1183/23120541.00402-2020. eCollection 2020 Oct.

Authors

Ryuta Baba¹, Kenji Oki¹, Kiyotaka Itcho¹, Kazuhiro Kobuke¹, Gaku Nagano¹, Haruya Ohno¹, Masayasu Yoneda¹, Noboru Hattori¹

Affiliation

¹ Dept of Molecular and Internal Medicine, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.

Abstract

Pulmonary expression of angiotensin-converting enzyme 2, which is a receptor of severe acute respiratory syndrome coronavirus 2, is not regulated by angiotensin II or renin-angiotensin system inhibitors #COVID19 https://bit.ly/3fkopuO.