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FEBS Lett. 1987 Aug 10;220(1):113-5.

Rapid changes of heat and desiccation tolerance correlated with changes of trehalose content in Saccharomyces cerevisiae cells subjected to temperature shifts.


The trehalose content of exponentially growing Saccharomyces cerevisiae cells rapidly increased in response to a temperature shift from 27 to 40 degrees C and decreased again when the temperature was shifted back from 40 to 27 degrees C. These changes were closely correlated with increases and decreases in the thermotolerance and desiccation tolerance of the cells. Our results support the hypothesis that trehalose functions as a protectant against heat and desiccation.

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