Simultaneous determination of ellagic and in Punica granatum, Myrtus communis and Itriphal formulation by an electrochemical sensor based on a paste electrode modified with multi-walled carbon nanotubes

Sayed Mehdi Ghoreishi; Mohsen Behpour; Maryam Khayatkashani; Mohamad Hasan Motaghedifard

doi:10.1039/c0ay00691b

Simultaneous determination of ellagic and in Punica granatum, Myrtus communis and Itriphal formulation by an electrochemical sensor based on a paste electrode modified with multi-walled carbon nanotubes

Anal Methods. 2011 Mar 1;3(3):636-645. doi: 10.1039/c0ay00691b.

Authors

Sayed Mehdi Ghoreishi¹, Mohsen Behpour¹, Maryam Khayatkashani¹, Mohamad Hasan Motaghedifard¹

Affiliation

¹ Department of Analytical Chemistry, Faculty of Chemistry, University of Kashan, Kashan, I.R. Iran. s.m.ghoreishi@kashanu.ac.ir.

PMID: 32938084
DOI: 10.1039/c0ay00691b

Abstract

An electrochemical method for the determination of ellagic acid (EA) and gallic acid (GA) was successfully applied to extracts of Punica granatum, Myrtus communis, and to Itriphal, a herbal formulation. The voltammetric determination of EA and GA was conducted with a novel sensor based on a modified carbon paste electrode with multi-walled carbon nanotubes. The electrochemical behavior of EA and GA at the modified sensor was characterized by cyclic voltammetry, chronocoulometry, linear sweep voltammetry, differential pulse voltammetry and rotating disk electrode voltammetry. Electrochemical parameters such as the diffusion coefficient (D), electron transfer coefficient (α), electron transfer rate constant (k) and ionic exchange current density (Io) were determined for EA and GA oxidation. The detection limit of GA was 0.2 μM and for EA was 0.21 nM over the 180 s accumulation time of the open circuit potential, respectively.