Eighty consecutive cases of gamete intra-fallopian transfer.
Department of Obstetrics and Gynaecology, National University Hospital, Republic of Singapore.
Eighty patients with the main problems of unexplained infertility, oligospermia and endometriosis were treated with gamete intra-Fallopian transfer (GIFT). From 80 treatment cycles, 29 women conceived (36.3%). Of these, four were biochemical pregnancies and therefore the clinical pregnancy rate (25/80) was 31.2%. There were six sets of multiple pregnancies, a multiple pregnancy rate of 24%. Three women (12%) miscarried. The pregnancy rates in the patients with unexplained infertility, oligospermia and endometriosis were 33.3, 16.7 and 38.5%, respectively. The transfer of four oocytes appears to increase the pregnancy rate without increasing the risk of multiple pregnancy. The presence of in-vitro fertilization of excess oocytes after GIFT did not correlate with the final outcome of GIFT.
PMID: 3281968 [PubMed - indexed for MEDLINE]