Acta Orthop Scand. 1988 Feb;59(1):56-62.

Chemonucleolysis for sciatica. A critical review.

Source

Department of Orthopedics, University of Gothenburg, Sahlgren Hospital, Sweden.

Abstract

Intradiscal injection of chymopapain for the treatment of sciatica due to disc herniation has been used for more than 25 years, but is still under debate. We review the indications, complications, and clinical results, and discuss the tissue effects of chymopapain. The results following surgical disc removal versus chymopapain injection indicate that surgery with removal of the disc hernia through a small laminotomy remains the documented treatment of choice for patients with proven disc herniation and sciatica in whom conservative treatment has failed.

Comment in

Acta Orthop Scand. 1989 Apr;60(2):235-8.

PMID:: 3281406; [PubMed - indexed for MEDLINE]

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Review

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Substances

Chymopapain

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