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    Pediatr Clin North Am. 1988 Feb;35(1):1-15.

    Host defense development in gut and related disorders.

    Source

    Harvard Medical School, Boston, Massachusetts.

    Erratum in

    • Pediatr Clin North Am 1988 Oct;35(5):preceding 953.

    Abstract

    The gastrointestinal tract serves as an important interface between ingested elements from the external environment and the internal milieu of the person. Maturation of this intestinal barrier appears to occur along with the normal development of other organ systems. Evidence is presented for this maturational process, and the relation of this immature barrier to certain disease states seen in the neonatal period (e.g., infectious diarrhea, necrotizing enterocolitis, and allergic disease) is discussed.

    PMID:
    3277127
    [PubMed - indexed for MEDLINE]

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