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J Oral Maxillofac Surg. 1988 Feb;46(2):128-33.

In vitro effects of low intensity direct current generated silver on eukaryotic cells.

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  • 1Department of Oral and Maxillofacial Surgery, Strong Memorial Hospital, Rochester, New York.


An examination of the effects of low intensity direct current generated silver, (LIDC Ag) on several types of eukaryotic microorganisms and cell culture lines suggests that LIDC Ag has an appropriate selective toxicity for prokaryotic cells. It appears that levels of this agent could be obtained clinically that would have marked bacteriostatic activity and yet have little or no effect on mammalian cells.

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